Scientific Director Pathology-00000PKS
Description
Janssen Pharmaceutical Company, a member of the Johnson & Johnson Family of Companies, is recruiting an experienced Veterinary Anatomic Pathologist, at the Scientific Director level to join the Tox/Path/LAM Team within Pre-Clinical Development and Safety (PD&S).
The position will be based in Beerse Belgium. The successful candidate will work on a global basis to deliver scientific support to Drug Discovery, Development Projects and Investigative Problem solving Teams.
Janssen Pharmaceutical Research & Development develops novel and innovative treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets for small and large molecules (Biologics) in Neuroscience, Oncology, Cardiovascular & Metabolism Disorders, Immunology and Infectious Diseases and Vaccines.
As a Scientific Director, Pathologist, you will be responsible for the following:
- Support drug discovery and development by providing scientific input in the design and conduct of toxicology experiments that focus on characterizing the safety of novel therapeutic targets and/or understanding potential mode of action for toxicity in pre-clinical studies.
- Review study protocols and make recommendations regarding the design of the clinical pathology and anatomic pathology portions of toxicology studies.
- Conduct gross and microscopic examinations of animal tissues from toxicology and investigative studies, interpret and explore the significance of results for clinical pathology, organ weight, necropsy, and histopathology data. Present pathology data/results at Discovery and Development research project team meetings.
- Provide concise written pathology reports that accurately and completely reflects the data collected and the significance/impact on candidate drug development, drug registration and human safety.
- Strong interest, knowledge and expertise in Molecular Pathology Techniques and leverage this to provide investigative pathology scientific leadership to drug discovery teams.
- Work collaboratively (locally and globally) with In Vitro Toxicology Sections and Investigative & Mechanistic Toxicology, PDM (Pharmacokinetics, Disposition and Metabolism), Laboratory Animal Medicine and other groups within Discovery Sciences to investigate mechanisms of toxicity of experimental, investigational and clinical development drug candidates.
- Ability to develop and implement research plans that will address complex issues/projects (involving molecular biology, targeted therapeutics, new and/or innovative assays to define both on- and off-target effects), and foresee the technical demands that will be required to provide definitive answers to key toxicology questions.
- Identify and lead collaborative scientific efforts with internal, external, consortia and academic investigators.
- Contribute to the identification of new safety biomarkers and assist in the design and execution of appropriate pre-clinical validation studies.
- Initiate and create plans for the implementation of new technologies in anatomic and clinical pathology.
Qualifications
- The successful candidate must have a DVM and preferably a Ph.D, and is board certified by the American/European College of Veterinary Pathologists (ACVP/ECVP) and/or FRCPath.
- A solid scientific publication record, 7-8 years of experience in the field of toxicological pathology and experience in conducting GLP toxicology studies is desirable.
- Excellent communication, project management skills and recognized knowledge and expertise in the field of pathology is required.
What’s in it for you …?
“Caring for the world, one person at a time…”
As an employee we consider you as our most valuable asset. We take your career seriously.
As part of a global team in an innovative environment your development is key and our day-to-day responsibility.
Through e-university, on the job training, various projects and programs, we ensure your personal growth.
Our benefits make sure we care for you and your family now and in the future.
Primary Location:Europe/Middle East/Africa-Belgium-Antwerp-Beerse
Organization: Janssen Pharmaceutica N.V. (7555)
Job Function: Drug & Product Safety Science
Description
Janssen Pharmaceutical Company, a member of the Johnson & Johnson Family of Companies, is recruiting an experienced Veterinary Anatomic Pathologist, at the Scientific Director level to join the Tox/Path/LAM Team within Pre-Clinical Development and Safety (PD&S).
The position will be based in Beerse Belgium. The successful candidate will work on a global basis to deliver scientific support to Drug Discovery, Development Projects and Investigative Problem solving Teams.
Janssen Pharmaceutical Research & Development develops novel and innovative treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets for small and large molecules (Biologics) in Neuroscience, Oncology, Cardiovascular & Metabolism Disorders, Immunology and Infectious Diseases and Vaccines.
As a Scientific Director, Pathologist, you will be responsible for the following:
- Support drug discovery and development by providing scientific input in the design and conduct of toxicology experiments that focus on characterizing the safety of novel therapeutic targets and/or understanding potential mode of action for toxicity in pre-clinical studies.
- Review study protocols and make recommendations regarding the design of the clinical pathology and anatomic pathology portions of toxicology studies.
- Conduct gross and microscopic examinations of animal tissues from toxicology and investigative studies, interpret and explore the significance of results for clinical pathology, organ weight, necropsy, and histopathology data. Present pathology data/results at Discovery and Development research project team meetings.
- Provide concise written pathology reports that accurately and completely reflects the data collected and the significance/impact on candidate drug development, drug registration and human safety.
- Strong interest, knowledge and expertise in Molecular Pathology Techniques and leverage this to provide investigative pathology scientific leadership to drug discovery teams.
- Work collaboratively (locally and globally) with In Vitro Toxicology Sections and Investigative & Mechanistic Toxicology, PDM (Pharmacokinetics, Disposition and Metabolism), Laboratory Animal Medicine and other groups within Discovery Sciences to investigate mechanisms of toxicity of experimental, investigational and clinical development drug candidates.
- Ability to develop and implement research plans that will address complex issues/projects (involving molecular biology, targeted therapeutics, new and/or innovative assays to define both on- and off-target effects), and foresee the technical demands that will be required to provide definitive answers to key toxicology questions.
- Identify and lead collaborative scientific efforts with internal, external, consortia and academic investigators.
- Contribute to the identification of new safety biomarkers and assist in the design and execution of appropriate pre-clinical validation studies.
- Initiate and create plans for the implementation of new technologies in anatomic and clinical pathology.
Qualifications
- The successful candidate must have a DVM and preferably a Ph.D, and is board certified by the American/European College of Veterinary Pathologists (ACVP/ECVP) and/or FRCPath.
- A solid scientific publication record, 7-8 years of experience in the field of toxicological pathology and experience in conducting GLP toxicology studies is desirable.
- Excellent communication, project management skills and recognized knowledge and expertise in the field of pathology is required.
What’s in it for you …?
“Caring for the world, one person at a time…”
As an employee we consider you as our most valuable asset. We take your career seriously.
As part of a global team in an innovative environment your development is key and our day-to-day responsibility.
Through e-university, on the job training, various projects and programs, we ensure your personal growth.
Our benefits make sure we care for you and your family now and in the future.
Primary Location:Europe/Middle East/Africa-Belgium-Antwerp-Beerse
Organization: Janssen Pharmaceutica N.V. (7555)
Job Function: Drug & Product Safety Science